WHO SHOULD TAKE TENOFOVIR?

Tenofovir is a nucleotide analog reverse transcriptase inhibitor, or nuke. These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme changes HIV’s genetic material (RNA) into the form of DNA. This has to occur before HIV’s genetic code gets inserted into an infected cell’s genetic codes.

Tenofovir was approved in 2001 as an antiretroviral drug (ARV) for people with HIV infection. It has not been carefully studied in people younger than 18 or older than age 65. In US treatment guidelines (see fact sheet 404), tenofovir is listed as a preferred drug for people just starting ART.

Tenofovir is used in combination with other antiviral medications to treat human immunodeficiency virus (HIV) in patients with acquired immunodeficiency syndrome (AIDS). Tenofovir is in a class of antiviral medications called reverse transcriptase inhibitors. It works by slowing the spread of HIV in the body. Tenofovir is not a cure and may not decrease the number of HIV-related illnesses. Tenofovir does not prevent the spread of HIV to other people.

Tenofovir comes as a tablet to take by mouth. It is usually taken once a day with a meal. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tenofovir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

This HIV treatment information is for educational purposes only and is not intended to replace the advice of your doctor or health care provider. We encourage you to discuss with your doctor any questions or concerns you may have.

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