Lamivudine is a prescription medicine used for the treatment of chronic hepatitis B, HIV, and AIDS. While the antiviral medication cannot cure these conditions, it can help prevent the HIV and hepatitis B viruses from multiplying. Lamivudine is in a class of prescriptions called nucleoside reverse transcriptase inhibitors. It works by stopping the spread of the HIV and hepatitis B viruses. Lamivudine is being manufactured by Glaxo Smith Kline Pharmaceuticals and available in 150mg and 300mg tablets. Lamivudine may also be used for relieve other conditions that determined by your doctor or consultant.

Lamivudine is useful in a wide range of patients with chronic hepatitis B and ongoing viral replication. In patients with compensated liver disease treated for 52 weeks in multicenter randomized, double-blind clinical studies, lamivudine 100 mg/day inhibited hepatitis B virus (HBV) replication, normalized ALT levels, produced significant reductions in hepatic necroinflammatory activity and halted the progression of fibrosis compared with placebo. Lamivudine is found in breast milk. Lamivudine is given at a dose of 100 mg daily for 52 weeks (21 ). Factors which should be considered in choosing an appropriate regimen include age, pre-treatment liver histology (amount of fibrosis), HBV viral load, and the potential side effects of the drugs (33 ).

Lamivudine is a nucleoside analogue that can directly suppress HBV replication. Despite promising results achieved in the treatment of chronic hepatitis B, whether early administration of lamivudine (prophylactic or therapeutic?) can prevent HBV reactivation after chemotherapy is still uncertain. Lamivudine is a useful treatment for chronic hepatitis B, but its usefulness as a single therapy is limited by the frequency with which resistance occurs. It will be important to ascertain how treatment outcomes can be improved by further insights into immune responsiveness during antiviral therapy. Lamivudine is used in the treatment of AIDS, usually in combination with AZT and/or other drugs. Although these drugs will not lead to a cure of this deadly malady, they do help slow down the destruction of the immune system by the AIDS virus.

Lamivudine is a potent reverse transcriptase inhibitor of the class nucleoside analog reverse transcriptase inhibitor (NARTI). Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. Lamivudine is one of a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). Reverse transcriptase is a part of HIV required to infect cells and make more viruses. Lamivudine is an antiviral medication. It is in a group of human immunodeficiency virus (HIV) medicines called reverse transcriptase inhibitors.

Lamivudine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse transcriptase enzyme. Lamivudine is taken together with zidovudine (AZT) or other medications used to treat HIV. Lamivudine is administered orally, and it is rapidly absorbed with a bio-availability of over 80%. Some research suggests that lamivudine can cross the blood-brain barrier .

Lamivudine PK parameters were significantly related to age. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors. It works by stopping the spread of the HIV and hepatitis B viruses. Lamivudine/zidovudine fixed dose combination tablets are a version of the already approved Combivir tablets manufactured by GlaxoSmithKline, and nevirapine tablets are a version of Viramune tablets manufactured by Boehringer-Ingelheim. The new co-packaged product consists of two tablets (lamivudine/zidovudine and nevirapine) each to be taken twice daily, after the initial two-week initiation phase of this nevirapine regimen.

This HIV treatment information is for educational purposes only and is not intended to replace the advice of your doctor or health care provider. We encourage you to discuss with your doctor any questions or concerns you may have.

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